Breakthrough in fight against diabetes
Scientists believe a variation in the gene's DNA promotes insulin resistance, the primary cause of type 2 diabetes, which affects two million people in the UK. The discovery could lead to new drug treatments that target the genetic fault and prevent the body failing to respond to insulin. The hormone controls the way cells absorb glucose from the blood and use it to generate energy. In type 2 diabetes, insulin often continues to be produced by the pancreas but it cannot be used properly. The new genetic link, the first known to involve insulin resistance, was found after scientists screened the DNA of more than 14,000 people.